Primitive mesenteric gastrointestinal stromal tumor with autonomic nerve/ganglionic differentiation presenting as a huge mass with synchronous nodules

Basile A, Kettenback J, Mundo E, Natoli A, Caloggero S, Minciullo M, Garito A
European Radiology 2005; advance online pre-publication 2/22/05
PubMed ID 15726376
Entrez PubMed

mTOR-targeted therapy of cancer with rapamycin derivatives --

Vignot et al.
Annals of Oncology 2005, e-pub advance access online
not yet catalogued in PubMed
Annals of Oncology

Recurrent GI bleeding and surgery following the initial response to imatinib therapy in GIST of the stomach

El Hajj II, Chehal A, El Saghir NS.
Dig Dis Sci. 2005 Jan;50(1):65-9. No abstract available.
PMID: 15712639
Entrez PubMed

Imatinib mesylate in the treatment of gastrointestinal stromal tumour

Steinert DM, McAuliffe JC, Trent JC.
Expert Opinion Pharmacotherapy 2005 Jan;6(1):105-13.
PMID: 15709888
Entrez PubMed

Gastrointestinal stromal tumor of the prostate

Van der Aa F, Sciot R, Blyweert W, Ost D, Van Poppel H, Van Oosterom A, Debiec-Rychter M, De Ridder D.
Urology. 2005 Feb;65(2):388.
PMID 15708062
Entrez PubMed

NCCN Soft Tissue Sarcoma Clinical Practice Guidelines in Oncology - version 1.2005

This flow-chart guideline from the National Comprehensive Cancer Network deals with GIST as well as other sarcomas. It is a 49-page Adobe pdf document. For GIST, see especially the flow charts on pages 1-20 and the text on pages 37-39.
Free access via National Comprehensive Cancer Network website.
You must go through a series of steps at the NCCN website to access this document.
First link to NCCN
NCCN
Then click "NCCN Clinical Practice Guidelines in Oncology."
Then click "NCCN Complete Library of Clinical Practice Guidelines Online."
Scroll to the bottom of the "agreement" page and click "I agree."
On the next page scrool down to Cancer by Site and click "Soft Tissue Sarcoma" in the right-hand column.
This will begin downloading the Adobe pdf document for you to view or print.
If you get lost in those steps, here is a direct link.
NCCN Soft Tissue Sarcoma Guidelines v1.2005

KIT and Platelet-Derived Growth Factor Receptor Alpha Tyrosine Kinase Gene Mutations and KIT Amplifications in Human Solid Tumors

Sihto H, Sarlomo-Rikala M, Tynninen O, Tanner M, Andersson LC, Franssila K, Nupponen NN, Joensuu H.
Journal of Clinical Oncology 2005; 23 (1): 49-57
PMID 1554568
free access via publisher
Journal of Clinical Oncology

Imatinib inhibits the functional capacity of cultured human monocytes.

Dewar AL, Doherty KV, Hughes TP, Lyons AB
Immunology and Cell Biology 2005 Feb;83(1):48-56.
PMID 15661041
This paper describes immunosuppressive effects of imatinib and suggests that there may be some other kinases inhibited besides kit to account for this effect.
Entrez PubMed

Treatment of GIST with imatinib mesylate: a major breakthrough in the understanding of tumor-specific molecular characteristics

de Mestier P, Guetz GD.
World J Surg. 2005 March; 29(3):357-361 discussion 362.
PMID 15706444
Entrez PubMed

The value of PET, CT and in-line PET/CT in patients with gastrointestinal stromal tumours: long-term outcome of treatment with imatinib mesylate

Goerres GW, Stupp R, Barghouth G, Hany TF, Pestalozzi B, Dizendorf E, Schnyder P, Luthi F, von Schulthess GK, Leyvraz S.
Eur J Nucl Med Mol Imaging. 2005 Feb;32(2):153-62.
PMID 15690223
Entrez PubMed

PDGFRalpha- and c-kit-mutated gastrointestinal stromal tumours (GISTs) are characterized by distinctive histological and immunohistochemical features

Pauls K, Merkelbach-Bruse S, Thal D, Buttner R, Wardelmann E.
Histopathology. 2005 Feb;46(2):166-75.
PMID 15693889
Entrez PubMed

Gastrointestinal stromal tumor (GIST) in southern Taiwan: A clinicopathologic study of 93 resected cases

Li C-F, Chuang S-S, Lu C-L, Lin C-N
Pathology - Research and Practice 2005; 201(1) 1-9.
PMID 15807305
Entrez PubMed

Carney triad: case report and molecular analysis of gastric tumor

J Diment, E Tamborini, P Casali, A Gronchi, JA Carney, M Colecchia
Human Pathology 2005; 36:112-116.
not yet in PubMed
see abstract at journal
Human Pathology

Loss of p16 Protein Defines High-Risk Patients with Gastrointestinal Stromal Tumors: A Tissue Microarray Study

Schneider-Stock et al.
Clinical Cancer Research 11(2):638.
Clinical Cancer Research

A case of pediatric gastrointestinal stromal tumor of the stomach

Iwasaki M, Morimoto T, Sano K, Fukumitsu K, Takeda R, Iwata S, Nakamura Y, Yasui H, Urata Y, Mukaihara S.
Pediatr Int. 2005 Feb;47(1):102-4.
PMID: 15693878
no abstract
Entrez PubMed

Some lessons learned from imatinib mesylate clinical development in gastrointestinal stromal tumors

Casali PG, Bertulli R, Fumagalli E, Coco P, Grosso F, Stacchiotti S.
Journal of Chemotherapy 2004 Nov;16 Suppl 4:55-8.
PMID 15688611
Entrez PubMed

Primary gastrointestinal stromal tumor of the esophagus in an HIV-positive patient

Padula A, Chin NW, Azeez S, Resetkova E, Andriko JA,
Miettinen M.
Annals of Diagnostic Pathology 2005 Feb;9(1):49-53.
PMID 15692952
This is a case report of a rare esophageal GIST.
Entrez PubMed

Digestive PEComas: a solution when the diagnosis fails to "fit".

Genevay M, Mc Kee T, Zimmer G, Cathomas G, Guillou L.
Ann Diagn Pathol. 2004 Dec;8(6):367-72.
PMID 15614743
This paper describes differential diagnosis of PEComa versus GIST.
Entrez PubMed

Correlation of KIT and platelet-derived growth factor receptor alpha mutations with gene activation and expression profiles in GISTs

Kang HJ, Nam SW, Kim H, Rhee H, Kim NG, Kim H, Hyung WJ, Noh SH, Kim JH, Yun CO, Liu ET, Kim H.
Oncogene. 2005 Feb 3;24(6):1066-1074.
PMID 15690055
Entrez PubMed

Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of PKC412 inhibitor against imatinib-resistant mutants

Debiec-Rychter M, Cools J, Dumez H, Sciot R, Stul M, Mentens N, Vranckx H, Wasag B, Prenen H, Roesel J, Hagemeijer A, Van Oosterom A, Marynen P.
Gastroenterology. 2005 Feb;128(2):270-9.
PMID 15685537
This paper describes how tumor cells obtained by biopsy from imatinib-resistant tumors of patients displayed different resistance-producing mutations. Most mutant cell types did respond to the drug PKC412 in lab tests. A variety of cellular mechanisms for imatinib resistance were identified.
Entrez PubMed

Gigantic gastrointestinal stromal tumor in the pelvis

Adachi Y, Yamamoto H, Nosho K, Tanimura A, Yuasa H, Ishi Y, Imai K, Kato Y.
Int J Colorectal Dis. 2005 Mar;20(2):196-8.
No abstract available.
PMID: 15338168
Entrez PubMed

Phase I-II trial of ONYX-015 in combination with MAP chemotherapy in patients with advanced sarcomas

Galanis E, Okuno SH, Nascimento AG, Lewis BD, Lee RA, Oliveira AM, Sloan JA, Atherton P, Edmonson JH, Erlichman C, Randlev B, Wang Q, Freeman S, Rubin J.
Gene Ther. 2005 Jan 13; [Epub ahead of print]
PMID 15647767
Entrez PubMed