Saturday, April 30, 2005

The unique simultaneous occurrence of granular cell tumor, gastrointestinal stromal tumor, and gastric adenocarcinoma.

Sailors JL, French SW
Arch Pathol Lab Med 2005 May; 129(5):e121-3.
PMID 15859656
Entrez PubMed

Thursday, April 28, 2005

Receptor Tyrosine Kinases and Anticancer Therapy

Medinger M, Drevs J.
Curr Pharm Des. 2005;11(9):1139-1149.
PMID 15853662
Entrez PubMed

Nursing implications of imatinib as molecularly targeted therapy for gastrointestinal stromal tumors

Griffin JM, Amand MS, Demetri GD.
Clin J Oncol Nurs. 2005 Apr;9(2):161-9.
PMID: 15853160
Entrez PubMed

Imaging gastrointestinal stromal tumors

Hersh MR, Choi J, Garrett C, Clark R.
Cancer Control. 2005 Apr;12(2):111-115.
PMID 15855894
Free access in PubMed
Entrez PubMed

Sunday, April 24, 2005

Hypoxia-inducible Factor-1{alpha} is Associated with Risk of Aggressive Behavior and Tumor Angiogenesis in Gastrointestinal Stromal Tumor

Chen WT, Huang CJ, Wu MT, Yang SF, Su YC, Chai CY.
Japanese Journal of Clinical Oncology 2005 Apr;35(4):207-13.
PMID: 15845570
Entrez PubMed

Saturday, April 23, 2005

PDGFR expression in differential diagnosis between KIT-negative gastrointestinal stromal tumours and other primary soft-tissue tumours of the GI tract

Rossi G, Valli R, Bertolini F, Marchioni A, Cavazza A, Mucciarini C, Migaldi M, Federico M, Trentini GP, Sgambato A.
Histopathology. 2005 May;46(5):522-31.
PMID: 15842634
Entrez PubMed

Wednesday, April 20, 2005

Familial gastrointestinal stromal tumor syndrome: phenotypic and molecular features in a kindred.

Li FP, Fletcher JA, Heinrich MC, Garber JE, Sallan SE, Curiel-Lewandrowski C, Duensing A, van de Rijn M, Schnipper LE, Demetri GD.
J Clin Oncol. 2005 Apr 20;23(12):2735-43.
PMID: 15837988
Entrez PubMed

Gastrointestinal Stromal Tumors in Children and Young Adults: A Clinicopathologic, Molecular, and Genomic Study of 15 Cases and Review of the Literatu

Prakash S, Sarran L, Socci N, Dematteo RP, Eisenstat J, Greco AM, Maki RG, Wexler LH, Laquaglia MP, Besmer P, Antonescu CR.
J Pediatr Hematol Oncol. 2005 Apr;27(4):179-187.
PMID: 15838387
Entrez PubMed

[New orientations in the management of advanced, metastatic GIST: combination of surgery and systemic therapy with imatinib]

Catani M, De Milito R, Simi M.
Chir Ital. 2005 Jan-Feb;57(1):127-33. Italian.
PMID: 15832750
paper in Italian, abstract in English
Entrez PubMed

Case report: duodenal stromal tumor.

Akkus MA, Kismet K, Erel S, Adibelli MA, Pulat H.
Acta Gastroenterol Belg. 2005 Jan-Mar;68(1):95-7.
PMID 15832594
Entrez PubMed

Gastrointestinal Stromal Tumor: New Nodule-within-a-Mass Pattern of Recurrence after Partial Response to Imatinib Mesylate

Shankar S, Vansonnenberg E, Desai J, Dipiro PJ, Van Den Abbeele A,
Demetri GD.
Radiology. 2005 June; 235(3): 892-898.
PMID: 15833985
Entrez PubMed

Sunday, April 17, 2005

Role of cytochrome p450 activity in the fate of anticancer agents and in drug resistance : focus on tamoxifen, Paclitaxel and imatinib metabolism.

Rochat B.
Clin Pharmacokinet. 2005;44(4):349-66.
PMID: 15828850
This paper discusses how drug metabolism in the individual can affect drug efficacy.
Entrez PubMed

Estimation of the malignant potential of gastrointestinal stromal tumors: the value of contrast-enhanced coded phase-inversion harmonics US.

Fukuta N, Kitano M, Maekawa K, Chikugo T, Kudo M.
J Gastroenterol. 2005 Mar;40(3):247-55.
PMID 15830283
This paper describes an ultrasound imaging thechnique that may assist in predicting the probability of metastasis.
Entrez PubMed

Saturday, April 16, 2005

Clinical benefit of intermittent administration of imatinib in a patient with metastatic gastrointestinal stromal tumour.

Morabito A, Longo R, Carillio G, Bonginelli P, Vitale S, Gasparini G.
Clin Oncol (R Coll Radiol). 2005 Apr;17(2):96-7.
PMID: 15830571
Entrez PubMed

c-KIT mutation analysis for diagnosis of gastrointestinal stromal tumors in fine needle aspiration specimens.

Willmore-Payne C, Layfield LJ, Holden JA.
Cancer. 2005 Apr 8; [Epub ahead of print]
PMID: 15822120
Entrez PubMed

Role of poly(ADP-ribose) polymerase activity in imatinib mesylate-induced cell death.

Moehring A, Wohlbold L, Aulitzky WE, van der Kuip H.
Cell Death Differ. 2005 Apr 1; [Epub ahead of print]
PMID: 15818402
This paper discusses how imatinib may kill CML cells. Some of the information may be pertinent to GIST cells.
Entrez PubMed

Miscellaneous conditions of the appendix.

Misdraji J, Graeme-Cook FM.
Semin Diagn Pathol. 2004 May;21(2):151-63.
PMID: 15807474
GIST rarely may affect the appendix, as discussed in this paper.
Entrez PubMed

Normal and oncogenic forms of the receptor tyrosine kinase kit.

Lennartsson J, Jelacic T, Linnekin D, Shivakrupa R.
Stem Cells. 2005;23(1):16-43.
PMID: 15625120
Entrez PubMed

The development and application of imatinib.

Jones RL, Judson IR.
Expert Opin Drug Saf. 2005 Mar;4(2):183-91.
PMID: 15794712
Entrez PubMed

Macrophage colony-stimulating factor receptor c-fms is a novel target of imatinib.

Dewar AL, Cambareri AC, Zannettino AC, Miller BL, Doherty KV, Hughes TP, Lyons AB.
Blood. 2005 Apr 15;105(8):3127-32.
PMID: 15637141
Entrez PubMed

Pathological changes related to Imatinib treatment in a patient with a metastatic gastrointestinal stromal tumour.

Abdulkader I, Cameselle-Teijeiro J, Forteza J.
Histopathology. 2005 Apr;46(4):470-2.
No abstract available.
PMID: 15810964
Entrez PubMed

The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications...

Breedveld P, Pluim D, Cipriani G, Wielinga P, van Tellingen O, Schinkel AH, Schellens JH.
Cancer Res. 2005 Apr 1;65(7):2577-82.
PMID: 15805252
Entrez PubMed

Tyrosine kinase inhibitors and the dawn of molecular cancer therapeutics

Tibes R, Trent J, Kurzrock R.
Annu Rev Pharmacol Toxicol. 2005;45:357-84.
PMID: 15822181
Entrez PubMed

A mutation-created novel intra-exonic pre-mRNA splice site causes constitutive activation of KIT in human gastrointestinal stromal tumors.

Chen LL, Sabripour M, Wu EF, Prieto VG, Fuller GN, Frazier ML.
Oncogene. 2005 June 16; 24(26):4271-4280.
PMID: 15824741
Entrez PubMed

Sunday, April 10, 2005

[Treatment of patients with gastrointestinal stromal tumour with imatinib mesylate.]

Haugland HK, Jebsen NL, Mannelqvist M, Skar R, Eide J, Ovrebo K, Horn A, Jensen DK, Monge OR, Lilleng PK.
Tidsskr Nor Laegeforen. 2005 Apr 7;125(7):868-72.
article in Norwegian, abstract in English.
PMID: 15815732
Entrez PubMed

Clinicopathological and immunohistochemical features of extragastrointestinal stromal tumors: report of two cases.

Nakagawa M, Akasaka Y, Kanai T, Takabayashi T, Miyazawa N.
Surg Today. 2005;35(4):336-40.
PMID: 15815855
Entrez PubMed

Gastrointestinal stromal tumors (GIST).

Sugar I, Forgacs B, Istvan G, Bognar G, Sapy Z, Ondrejka P.
Hepatogastroenterology. 2005 Mar-Apr;52(62):409-13.
PMID: 15816446
Entrez PubMed

Friday, April 08, 2005

Acquired resistance to imatinib in gastrointestinal stromal tumours caused by multiple KIT mutations.

Wardelmann E, Thomas N, Merkelbach-Bruse S, Pauls K, Speidel N, Buttner R, Bihl H, Leutner CC, Heinicke T, Hohenberger P.
Lancet Oncol. 2005 Apr;6(4):249-51.
No abstract available.
PMID: 15811621
Entrez PubMed

Neoadjuvant therapy with imatinib mesylate for locally advanced GI stromal tumor

Shah JN, Sun W, Seethala RR, Livolsi VA, Fry RD, Ginsberg GG.
Gastrointest Endosc. 2005 Apr;61(4):625-7.
No abstract available.
PMID: 15812427
Entrez PubMed

Monday, April 04, 2005

Role of c-Kit and erythropoietin receptor in erythropoiesis

Munugalavadla V, Kapur R.
Crit Rev Oncol Hematol. 2005 Apr;54(1):63-75.
PMID: 15780908
This paper discusses how KIT is involved in the body's production of red blood cells. This is relevant to how Gleevec, which inhibits KIT, can cause anemia.
Entrez PubMed

Life-threatening severe allergic reactions: urticaria, angioedema, and anaphylaxis.

Lipozencic J, Wolf R.
Clin Dermatol. 2005 Mar-Apr;23(2):193-205.
PMID: 15802213
Though rare, serious skin reactions to Gleevec can occur.
This paper discusses serious dermatologic reactions, including to Gleevec.
Entrez PubMed

Saturday, April 02, 2005

Cellular hamartoma resembling gastrointestinal stromal tumor: a solid tumor of the pancreas expressing c-kit (CD117).

Pauser U, da Silva MT, Placke J, Klimstra DS, Kloppel G.
Mod Pathol. 2005 Apr 1; [Epub ahead of print]
PMID 15803185
This paper describes a tumor which could be confused with GIST.
Entrez PubMed

Gastrointestinal stromal tumors: a clinicopathologic and immunohistochemical study of 136 cases

Orosz Z, Tornoczky T, Sapi Z.
Pathol Oncol Res. 2005;11(1):11-21. Epub 2005 Mar 31.
PMID: 15800677
free access in PubMed
Entrez PubMed

Gastrointestinal stromal tumor (GIST) of stomach in a pediatric patient

Egloff A, Lee EY, Dillon JE.
Pediatr Radiol. 2005 July; 35(7):728-729.
PMID: 15800780
no abstract
Entrez PubMed

Friday, April 01, 2005

Imatinib-induced sweet syndrome in a patient with chronic myeloid leukemia

Ayirookuzhi SJ, Ma L, Ramshesh P, Mills G.
Arch Dermatol. 2005 Mar;141(3):368-70.
PMID: 15781678
Though not about GIST, this paper describes a skin reaction to Gleevec.
Entrez PubMed

[Clinicopathological and immunohistochemical study of extra-gastrointestinal stromal tumors arising from the omentum and mesentery.]

Li ZY, Huan XQ, Liang XJ, Li ZS, Tan AZ.
Zhonghua Bing Li Xue Za Zhi. 2005 Jan;34(1):11-4.
Abstract in English, paper in Chinese.
PMID: 15796875
Entrez PubMed

[Gastrointestinal stromal tumor: a clinicopathological study of 74 cases.]

Yang QC, Ji XH, Shen Y, Han F, Zhang XJ, Liu HB.
Zhonghua Bing Li Xue Za Zhi. 2005 Jan;34(1):6-10.
Abstract in English, paper in Chinese.
PMID: 15796874
Entrez PubMed

Clinical pharmacokinetics of imatinib mesylate

Leveque D, Maloisel F.
In Vivo. 2005 Jan-Feb;19(1):77-84.
PMID: 15796158
Entrez PubMed

Role of CT in the follow-up of hepatic and peritoneal metastases of GIST under imatinib mesylate treatment: a prospective study of 54 patients

Vanel D, Albiter M, Shapeero L, Le Cesne A, Bonvalot S, Le Pechoux C, Terrier P, Petrow P, Caillet H, Dromain C.
Eur J Radiol. 2005 Apr;54(1):118-23.
PMID: 15797301
Entrez PubMed