Phase I Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PTK787/ZK 222584 in Patients With Advanced Cancer

Thomas AL, Morgan B, Horsfield MA, Higginson A, Kay A, Lee L, Masson E, Laurent D, Steward WP.
J Clin Oncol. 2005 May 2; [Epub ahead of print]
PMID: 15867205
This drug, though only in Phase I testing at this stage, could potentially be useful against GIST in the future if it performs well in Phase II trials. It is active against c-kit as well as angiogenic targets.
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Immunohistochemical profile and c-kit mutations in gastrointestinal stromal tumors.

Romagnoli S, Graziani D, Bramerio M, Gambacorta M, Colombo P, Roncalli M, Coggi G, Bosari S.
Pathol Res Pract. 2005;201(2):71-81.
PMID 15901127
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Gastrointestinal stromal tumors: a seldom diagnosed cause of severe anemia.

Lucchetta MC, Liberati G, Petraccia L, Campanella J, Grassi M.
Dig Dis Sci. 2005 May;50(5):815-9.
No anstract available.
PMID: 15906750
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A rare case of rapid growth of exophytic gastrointestinal stromal tumor of the stomach.

Ding G, Yang J, Cheng S, Kai L, Nan L, Zhang S, Cong W, Wu M.
Dig Dis Sci. 2005 May;50(5):820-3.
No absrtact available.
PMID: 15906751
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The expression of p53 and bcl-2 in GISTs is associated with anatomical site, and p53 expression is associated with grade and cinical outcome

Feakins RM.
Histopathology. 2005 Mar;46(3):270-9.
PMID: 15720412
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Gastrointestinal stromal tumors in Iceland, 1990-2003: The Icelandic GIST study, a population-based incidence and pathologic risk stratification study

Tryggvason G, Gislason HG, Magnusson MK, Jonasson JG.
Int J Cancer. 2005; 117:289-293.
PMID: 15900576
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Resection of residual disease in patients with metastatic gastrointestinal stromal tumors responding to treatment with imatinib.

Bauer S, Hartmann JT, de Wit M, Lang H, Grabellus F, Antoch G, Niebel W, Erhard J, Ebeling P, Zeth M, Taeger G, Seeber S, Flasshove M, Schutte J.
Int J Cancer. 2005; 117:316-325
PMID: 15900603
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Gastrointestinal Stromal Tumors of Neurofibromatosis Type I (von Recklinghausen's Disease).

Takazawa Y, Sakurai S, Sakuma Y, Ikeda T, Yamaguchi J, Hashizume Y, Yokoyama S, Motegi A, Fukayama M.
Am J Surg Pathol. 2005 Jun;29(6):755-763.
PMID: 15897742
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Molecularly targeted therapy for gastrointestinal cancer.

Wiedmann MW, Caca K.
Curr Cancer Drug Targets. 2005 May;5(3):171-93.
PMID 15892618
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Epithelioid Gastrointestinal Stromal Tumor With PDGFRA Activating Mutation and Immunoreactivity.

Yi ES, Strong CR, Piao Z, Perucho M, Weidner N.
Appl Immunohistochem Mol Morphol. 2005 Jun;13(2):157-161.
PMID 15894928
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Gastric GI stromal tumors (GISTs): The role of surgery in the era of targeted therapy.

Heinrich MC, Corless CL.
J Surg Oncol. 2005 May 13;90(3):195-207 discussion 207
PMID: 15895440
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Ruptured gastrointestinal stromal tumors: radiologic findings in six cases.

M. F. Cegarra-Navarro , M. A. Corral de la Calle, E. Girela-Baena, J. M. García-Santos, F. Lloret-Estañ and E. Parlorio de Andrés
Abdominal Imaging 2005 published online April 21.
PMID: 15834676
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KIT overexpression and amplification in gastrointestinal stromal tumors (GISTs).

Tabone S, Theou N, Wozniak A, Saffroy R, Deville L, Julie C, Callard P, Lavergne-Slove A, Debiec-Rychter M, Lemoine A, Emile JF.
Biochim Biophys Acta. 2005 Apr 13; [Epub ahead of print]
PMID 15869870
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Resistance to tyrosine kinase inhibitors: Calling on extra forces

Cools J, Maertens C, Marynen P.
Drug Resist Updat. 2005 June; 8(3):119-129.
PMID: 15869901
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Differential diagnosis of gastrointestinal leiomyoma versus gastrointestinal stromal tumor

Kuhlgatz J, Sander B, Golas MM, Gunawan B, Schulze T, Schulten HJ, Wardelmann E, Fuzesi L.
Int J Colorectal Dis. 2005 May 5; [Epub ahead of print]
PMID: 15875204
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Patterns of gene amplification in gastrointestinal stromal tumors (GIST).

Tornillo L, Duchini G, Carafa V, Lugli A, Dirnhofer S, Di Vizio D, Boscaino A, Russo R, Tapia C, Schneider-Stock R, Sauter G, Insabato L, Terracciano LM.
Laboratory Investigation. 2005 May 2; [Epub ahead of print]
PMID: 15864317
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Perforation of metastatic melanoma to the small bowel with simultaneous gastrointestinal stromal tumor

Brummel N, Awad Z, Frazier S, Liu J, Rangnekar N.
World J Gastroenterol. 2005 May 7;11(17):2687-9.
PMID: 15849837
Free access in PubMed.
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