PKC412 inhibits in vitro growth of neoplastic human mast cells expressing the D816V-mutated variant of KIT: comparison with AMN107, imatinib, and ...

Gleixner KV, Mayerhofer M, Aichberger KJ, Derdak S, Sonneck K, Bohm A, Gruze A, Samorapoompichit P, Manley PW, Fabbro D, Pickl WF, Sillaber C, Valent P.
Blood. 2005 Sep 27; [Epub ahead of print]
PMID: 16189265
Although this paper is based on mast cells, not GIST cells, it is relevant due to the different KIT mutations and corresponding drug sensitivities discussed.
Entrez PubMed

Oesophageal gastrointestinal stromal tumour masquerading as neuroendocrine carcinoma.

Feakins RM, Mears L, Atkinson P, Hughes F.
Histopathology. 2005 Sep;47(3):327-9.
No abstract available.
PMID: 16115239
Entrez PubMed

[Angiographic diagnosis of gastrointestinal stromal tumors.]

Fang SH, Meng L, Dong DJ, Zhang SZ, Jin M.
Zhonghua Zhong Liu Za Zhi. 2005 Aug;27(8):496-8.
abstract in English, paper in Chinese.
PMID: 16188152
Entrez PubMed

Endoscopic ultrasound-guided fine-needle aspiration of intramural and extraintestinal mass lesions: diagnostic accuracy, complication assessment...

Chen VK, Eloubeidi MA.
Endoscopy. 2005 Oct;37(10):984-9.
PMID: 16189771
Entrez PubMed

Immunohistochemical and molecular assessment of human herpesvirus type 8 in gastrointestinal tumours.

Su CC, Li CF, Liao YL, Lin CN, Lu JJ.
J Clin Pathol. 2005 Aug;58(8):856-9.
PMID: 16049289
Entrez PubMed

Resistance to imatinib, low-grade FDG-avidity on PET, and acquired KIT exon 17 mutation in gastrointestinal stromal tumour

Grimpen F, Yip D, McArthur G, Waring P, Goldstein D, Loughrey M, Beshay V, Chong G.
Lancet Oncol. 2005 Sep;6(9):724-7.
No abstract available.
PMID: 16129374
Entrez PubMed

Multiple gastrointestinal stromal tumors with a germline c-kit mutation

Kim HJ, Lim SJ, Park K, Yuh YJ, Jang SJ, Choi J.
Pathol Int. 2005 Oct;55(10):655-9.
PMID: 16185297
Entrez PubMed

Bronchogenic cyst of the gastric fundus presenting as a gastrointestinal stromal tumor.

Melo N, Pitman MB, Rattner DW.
J Laparoendosc Adv Surg Tech A. 2005 Apr;15(2):163-5.
PMID: 15898909
Entrez PubMed

Liver Metastases in Candidates for Hepatic Resection: Comparison of Helical CT and Gadolinium- and SPIO-enhanced MR Imaging

Ward J, Robinson PJ, Guthrie JA, Downing S, Wilson D, Lodge JP, Prasad KR, Toogood GJ, Wyatt JI.
Radiology. 2005 Aug 26; [Epub ahead of print]
PMID: 16126930
Entrez PubMed

Mesenteric cysts: a rare cause of abdominal pain.

Lockhart C, Kennedy A, Ali S, McManus D, Johnston SD.
Ulster Med J. 2005 May;74(1):60-2.
No abstract available.
PMID: 16022137
Entrez PubMed

Liver Metastases in Candidates for Hepatic Resection: Comparison of Helical CT and Gadolinium- and SPIO-enhanced MR Imaging

Ward J, Robinson PJ, Guthrie JA, Downing S, Wilson D, Lodge JP, Prasad KR, Toogood GJ, Wyatt JI.
Radiology. 2005 Aug 26; [Epub ahead of print]
PMID: 16126930
Entrez PubMed

The kinase inhibitor imatinib mesylate inhibits TNF-{alpha} production in vitro and prevents TNF-dependent acute hepatic inflammation

Wolf AM, Wolf D, Rumpold H, Ludwiczek S, Enrich B, Gastl G, Weiss G, Tilg H.
Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13622-7.
PMID: 16174751
Entrez PubMed

Quantification of Imatinib in Human Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry

Titier K, Picard S, Ducint D, Teilhet E, Moore N, Berthaud P, Mahon FX, Molimard M.
Ther Drug Monit. 2005 Oct;27(5):634-640.
PMID: 16175138
Entrez PubMed

Gastrointestinal Stromal Tumors of the Stomach in Children and Young Adults: A Clinicopathologic, Immunohistochemical, and Molecular Genetic Study

Miettinen M, Lasota J, Sobin LH.
Am J Surg Pathol. 2005 Oct;29(10):1373-1381.
PMID: 16160481
Entrez PubMed

Complete remission with imatinib in metastatic gastrointestinal stromal tumors

Chacon M, Roca E, Huertas E, Loria FS, Domenichini E.
J Clin Oncol. 2005 Sep 20;23(27):6801-2.
No abstract available.
This letter relates to an earlier case report of a patient with no evidence of living tumor cells in a tumor resected after Gleevec therapy. However, the patient did develop metastasis at a distant site afterward.
PMID: 16170193
Entrez PubMed

Complete remission with imatinib in metastastic gastrointestinal stromal tumors

Bauer S, Lang H, Schutte J, Hartmann JT.
J Clin Oncol. 2005 Sep 20;23(27):6800-1.
No abstract available.
PMID: 16170192
This letter discusses how a cold PET scan does not necessarily imply that there are no living tumor cells left in a tumor: usually there are still viable cells.
Entrez PubMed

Severe hypoglycemia caused by paraneoplastic production of igf-ii in patients with advanced gastrointestinal stromal tumors: a report of two cases

Pink D, Schoeler D, Lindner T, Thuss-Patience PC, Kretzschmar A, Knipp H, Vanhoefer U, Reichardt P.
J Clin Oncol. 2005 Sep 20;23(27):6809-11.
PMID: 16170199
This brief report describes low blood sugar in a GIST patient before diagnosis, which improved after diagnosis and start of Gleevec therapy.
No abstract available
Entrez PubMed

Enhancement of antitumor activity of the anti-EGF receptor monoclonal antibody cetuximab/C225 by perifosine in PTEN-deficient cancer cells.

Li X, Luwor R, Lu Y, Liang K, Fan Z.
Oncogene. 2005 Sep 19; [Epub ahead of print]
PMID: 16170346
This paper is not about GIST, but it tests the use of perifosine, a drug which is being tested against GIST in a combination clinical trial at MD Anderson.
Entrez PubMed

Gastrointestinal stromal tumors and the evolution of targeted therapy.

Sanborn RE, Blanke CD.
Clin Adv Hematol Oncol. 2005 Aug;3(8):647-57.
PMID: 16167051
Entrez PubMed

Biology, diagnosis and therapeutic options in gastrointestinal stromal tumours

Comandone A, Boglione A.
Minerva Chir. 2005 Aug;60(5):197-203.
PMID: 16166919
Entrez PubMed

Prognostic Role of E2F1 and Members of the CDKN2A Network in Gastrointestinal Stromal Tumors.

Haller F, Gunawan B, von Heydebreck A, Schwager S, Schulten HJ, Wolf-Salgo J, Langer C, Ramadori G, Sultmann H, Fuzesi L.
Clin Cancer Res. 2005 Sep 15;11(18):6589-97.
PMID: 16166437
Entrez PubMed

[Clinical analysis of prognostic factors for patients with gastrointestinal stromal tumors.]

Jie ZG, Xie XP, Qin KW, Liu Y, Li ZR, Dai AB, Yao YX.
Zhonghua Wei Chang Wai Ke Za Zhi. 2005 May;8(3):210-2.
abstract in Englih, paper in Chinese.
PMID: 16167229
Entrez PubMed

[Analysis of prognostic factors in gastrointestinal stromal tumors of the small intestine.]

Bai YK, Shao YF, Shi SS, Gao YN, Sun YT, Wan YL.
Zhonghua Wei Chang Wai Ke Za Zhi. 2005 May;8(3):213-6.
abstract in English, paper in Chinese.
PMID: 16167230
Entrez PubMed

Computed Tomography and Sonographic Findings of Hepatic Metastases From Gastrointestinal Stromal Tumors After Chemotherapy

Yang DM, Kim H, Kang JH, Park CH, Kim HS, Shin DB.
J Comput Assist Tomogr. 2005 September/October;29(5):592-595.
PMID: 16163025
Entrez PubMed

[Gastrointestinal stromal tumors. A study of 5 cases]

Mouna BB, Asma KZ, Afef K, Dalila G, Najet BH, Malika R, Jamel K, Abdeljabbar G, Olfa K, Achraf C, Mohamed BA, Slim K, Abdelmajid L.
Tunis Med. 2005 Jun;83(6):354-9.
abstract in English, paper in French.
PMID: 16156411
Entrez PubMed

GIST of the stomach in children and young adults: A clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases with followup...

Miettinen M, Lasota J, Sobin LH.
Am J Surg Pathol. 2005 Oct;29(10):1373-1381.
PMID: 16160481
Entrez PubMed

Gastrointestinal stromal tumors presenting as gynecological tumors

Hsu S, Chen SS, Chen YZ.
Eur J Obstet Gynecol Reprod Biol. 2005 Sep 10; [Epub ahead of print]
No abstract available.
PMID: 16159693
Entrez PubMed

[Imatinib mesylate STI571 therapy for five patients with advanced gastrointestinall stromal tumors.]

Shen KT, Hou YY, Qin XY, Song LJ, Sujie A.
Zhonghua Wei Chang Wai Ke Za Zhi. 2005 Mar;8(2):129-31.
abstract in English, paper in Chinese.
PMID: 16155822
Entrez PubMed

The great imitator: GIST mimicking malignant ovarian tumor

Hereter L, Pascual MA, Tresserra F, Fernandez-Cid M, Fabregas R.
Ultrasound Obstet Gynecol. 2005 Sep 8;26(4):428 [Epub ahead of print]
No Abstract.
PMID: 16152464
Entrez PubMed

Soft tissue sarcoma: advances in understanding and management

Brennan MF.
Surgeon. 2005 Jun;3(3):216-23. Review.
PMID: 16076008
Entrez PubMed

Bleeding stromal tumor.

Giesler T, Muller S, Schmiedehausen K, Hahn EG, Raithel M.
Gastrointest Endosc. 2005 Apr;61(4):593.
No abstract available.
PMID: 15812415
Entrez PubMed

[Gastrointestinal stromal tumors (GISTs): clinical and pathological features]

Kovacs M, Nagy P, Pak G, Feher J.
Orv Hetil. 2005 Jun 26;146(26):1375-81. Review.
abstract in English, paper in Hungarian
PMID: 16052979
Entrez PubMed

[GIST: a clinical case as a model of surgical and pharmacological therapy of solid tumours]

D'Amato A, Pezzoli F, Caterino S, Cavallini M, Balducci G, Bocchetti T, Ziparo V.
Chir Ital. 2005 Jul-Aug;57(4):509-14.
abstract in English, paper in Italian
PMID: 16060192
Entrez PubMed

[Difficulties in diagnosing and treating GIST: report and analysis of a case]

Testi W, Staffieri C, Consiglio FM, Genovese A, Cirianni D, Ranalli M, Bing C, Tumbiolo S.
Chir Ital. 2005 Jul-Aug;57(4):515-20.
abstract in English, paper in Italian
PMID: 16060193
Entrez PubMed

Primary gastrointestinal stromal tumor of the liver with lung metastases successfully treated with STI-571 (imatinib mesylate)

De Chiara A, De Rosa V, Lastoria S, Lastoria S, Franco R, Botti G, Iaffaioli VR, Apice G.
Front Biosci. 2006 Jan 1;11:498-501.
PMID: 16146747
Entrez PubMed

Effect of angiosonography to monitor response during imatinib treatment in patients with metastatic gastrointestinal stromal tumors

De Giorgi U, Aliberti C, Benea G, Conti M, Marangolo M.
Clin Cancer Res. 2005 Sep 1;11(17):6171-6.
PMID: 16144917
Angiosonography is an imaging method used here to evaluate blood supply in tumors.
Entrez PubMed

Effects of imatinib on normal hematopoiesis and immune activation

Appel S, Balabanov S, Brummendorf TH, Brossart P.
Stem Cells. 2005 Sep;23(8):1082-8.
PMID: 16140870
Entrez PubMed

A functional approach to questions about life, death, and phosphorylation

Bernards R.
Cancer Cell. 2005 Jun;7(6):503-4.
PMID: 15950899
This paper discusses Gleevec and similar future drugs.
Entrez PubMed

About the presence of interstitial cells of Cajal outside the musculature of the gastrointestinal tract

Huizinga JD, Faussone-Pellegrini MS.
J Cell Mol Med. 2005 Apr-Jun;9(2):468-73.
PMID: 15963266
free access paper
Entrez PubMed

Novel type of interstitial cell (Cajal-like) in human fallopian tube

Popescu LM, Ciontea SM, Cretoiu D, Hinescu ME, Radu E, Ionescu N, Ceausu M, Gherghiceanu M, Braga RI, Vasilescu F, Zagrean L, Ardeleanu C.
J Cell Mol Med. 2005 Apr-Jun;9(2):479-523.
PMID: 15963270
free access paper
Entrez PubMed

Sarcomas and pharmacogenetics

Biason P, Toffoli G.
Pharmacogenomics. 2005 Sep;6(6):585-601.
PMID: 16142999
Entrez PubMed

Gastrointestinal stromal tumors. A multicenter experience

Urbanczyk K, Limon J, Korobowicz E, Chosia M, Sygut J, Karcz D, Iwanik K, Osuch C, Lasota J, Stachura J.
Pol J Pathol. 2005;56(2):51-61.
PMID: 16092666
Entrez PubMed

Novel Germline Mutation of KIT Associated With Familial Gastrointestinal Stromal Tumors and Mastocytosis

Hartmann K, Wardelmann E, Ma Y, Merkelbach-Bruse S, Preussner LM, Woolery C, Baldus SE, Heinicke T, Thiele J, Buettner R, Longley BJ.
Gastroenterology. 2005 Sep;129(3):1042-6.
PMID: 16143141
Entrez PubMed

Pathophysiology, diagnosis, and treatment of gastrointestinal stromal tumors.

Shinomura Y, Kinoshita K, Tsutsui S, Hirota S.
J Gastroenterol. 2005 Aug;40(8):775-80.
PMID: 16143881
Entrez PubMed

Gastrointestinal Stromal Tumours in Patients with Other-Type Cancer: A Mere Coincidence or an Etiological Association? A Study of 97 GIST cases

Agaimy A, Wuensch PH.
Z Gastroenterol. 2005 Sep;43(9):1025-1030.
PMID: 16142610
Entrez PubMed

Perineurioma of the stomach. A rare spindle cell neoplasm that should be distinguished from gastrointestinal stromal tumor

Agaimy A, Wuensch PH.
Pathol Res Pract. 2005;201(6):463-7.
PMID: 16136753
This paper discusses differential diagnosis btween GIST and another rare tumor.
Entrez PubMed

Follow-up of gastro-intestinal stromal tumours (GIST) during treatment with imatinib mesylate by abdominal MRI

Stroszczynski C, Jost D, Reichardt P, Chmelik P, Gaffke G, Kretzschmar A, Schneider U, Felix R, Hohenberger P.
Eur Radiol. 2005 Dec; 15(12): 2448-2456.
PMID: 16132930
Entrez PubMed

The utility of fine-needle aspiration in the diagnosis of gastrointestinal stromal tumors

Elliott DD, Fanning CV, Caraway NP.
Cancer. 2005 Aug 29; [Epub ahead of print]
PMID: 16130141
Entrez PubMed

Compensatory PI3-kinase/Akt/mTor activation regulates imatinib resistance development

Burchert A, Wang Y, Cai D, von Bubnoff N, Paschka P, Muller-Brusselbach S, Ottmann OG, Duyster J, Hochhaus A, Neubauer A.
Leukemia. 2005 Sep 1; [Epub ahead of print]
PMID: 16136169
This paper is about Gleevec resistance in leukemia patients, but some of the same mechanisms could be relevant to GIST.
Entrez PubMed

Deletions Affecting Codons 557-558 of the c-KIT Gene Indicate a Poor Prognosis in Patients With Completely Resected Gastrointestinal Stromal Tumors: A

Martin J, Poveda A, Llombart-Bosch A, Ramos R, Lopez-Guerrero JA, Del Muro JG, Maurel J, Calabuig S, Gutierrez A, de Sande JL, Martinez J, De Juan A, Lainez N, Losa F, Alija V, Escudero P, Casado A, Garcia P, Blanco R, Buesa JM.
J Clin Oncol. 2005 Sep 1;23(25):6190-8.
PMID: 16135486
Entrez PubMed

Gastrointestinal stromal tumor: 5 years later

van der Zwan SM, Dematteo RP.
Cancer. 2005 Aug 31; [Epub ahead of print]
PMID: 16136600
Entrez PubMed

Curative endoscopic ultrasound-assisted submucosal resection of a gastric stromal tumor

Saftoiu A, Ciurea T, Georgescu CV, Comanescu V, Popescu C.
Rom J Gastroenterol. 2005 Jun;14(2):177-82.
PMID: 15990940
Entrez PubMed

Bleeding esophageal GIST

Manu N, Richard P, Howard S.
Dis Esophagus. 2005;18(4):281-2.
PMID: 16128787
Entrez PubMed

Signaling by Kit protein-tyrosine kinase-The stem cell factor receptor

Roskoski R Jr.
Biochem Biophys Res Commun. 2005 Aug 26; [Epub ahead of print]
PMID: 16129412
This paper describes signaling in normal KIT, thereby helping us understand what is different in mutated KIT involved in GISTs.
Entrez PubMed

An extramural gastrointestinal stromal tumor of the duodenum mimicking a pancreatic head tumor

Uchida H, Sasaki A, Iwaki K, Tominaga M, Yada K, Iwashita Y, Shibata K, Matsumoto T, Ohta M, Kitano S.
J Hepatobiliary Pancreat Surg. 2005;12(4):324-7.
PMID: 16133702
Entrez PubMed