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GIST Support International - Donating Tissue to Research
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Donating Tissue to Research on Pediatric, Carney Triad, and wildtype GIST

The samples of tumors removed from patients during surgery are extremely valuable to researchers who are striving to identify the causes of GIST in children, adolescents, and young adults.  Only when the cause has been identified can a cure be found. 

Two types of samples are helpful:

  • samples from past surgery
    • a paraffin block of tissue or unstained slides
    • can be requested through the pathology department o the hospital where the surgery was performed
  • samples from upcoming surgery
    • flash frozen tissue samples
    • must be requested through your surgeon and the pathology department prior to the operation.

If you are scheduling surgery for yourself or your child, please consider having frozen tissue samples saved to donate to research.  You can arrange for this through your surgeon if you mention it in advance.  If you can send archived samples from past surgeries, including unstained slides and paraffin blocks of tissue, those are also helpful.

Worthy researchers include the following (listed in alphabetical order).  Please contact the investigator for instructions on completing any needed paperwork and having the samples shipped. 


Cristina R. Antonescu, MD
Department of Pathology
Memorial Sloan-Kettering Cancer Center
1275 York Ave.
New York, NY  10021

Phone: 212-639-5721


J. Aidan Carney, MD, PhD, FRCP
Emeritus Professor of Pathology
Plummer North 10
Mayo Clinic
200 Southwest 1st Street
Rochester    MN 55905

Phone: 507-284-2691

Dr. Carney requests that tissue samples
be sent to Dr. Stratakis at the NIH (see
separate entry), his colleague and
research partner.  Dr. Carney continues
to work to establish the clinical,
pathological and behavioral characteristics
of pediatric GIST, with emphasis on familial
involvement and  associated conditions.

NIH Pediatric & Wildtype GIST Clinic
National Institutes of Health
Bethesda, MD 20892

Constantine A. Stratakis MD, D(Med)S
Chief, Section on Endocrinology and Genetics
National Institute for Child Health & Human

Fax: 301-402-0574/480-0378



Our goal is to identify genes and
therapies for pediatric GIST, familial GIST,
Carney Triad,  and related conditions in
the context of syndromes that are not due
to the known KIT and PDGFRA mutations.

Please e-mail Dr. Stratakis for instructions on
tissue donations.  You may download and
print a medical release form by clicking below:

Form for samples from prior surgery

Form for samples from upcoming surgery




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