GIST Support International - logo

Donating Tissue to Research
GIST Imagery

Donating Tissue to Research on Pediatric and Carney Triad GIST

The samples of tumors removed from patients during surgery are extremely valuable to researchers who are striving to identify the causes of GIST in children, adolescents, and young adults.  If you are scheduling surgery for yourself or your child, please consider having frozen tissue samples saved to donate to research.  Only when the cause has been identified can a cure be found. 

Worthy researchers include the following (listed in alphabetical order).  Please contact the investigator for instructions on completing any needed paperwork and having the samples shipped. 

Cristina R. Antonescu, MD
Department of Pathology
Memorial Sloan-Kettering Cancer Center
1275 York Ave.
New York, NY  10021

Phone: 212-639-5721
E-mail: 
antonesc@mskcc.org

J. Aidan Carney, MD, PhD, FRCP
Emeritus Professor of Pathology
Plummer North 10
Mayo Clinic
200 Southwest 1st Street
Rochester    MN 55905

Phone: 507-284-2691
Fax:507-284-5036
E-mail: carney.aidan@mayo.edu

Our goals are to identify the cause of
pediatric GIST, including our focus on
the familial form of the tumor, in order
to develop
1) designer drugs to treat the tumor
and its metastases
and
2)  molecular methods to prevent
emergence of the tumors in patients
who have the genetic trait to develop them.
Andrew K. Godwin, PhD
Director, Clinical Molecular Genetics Laboratory
(215-728-2756)
Director, Biosample Repository
Department of Medical Oncology
Fox Chase Cancer Center
Philadelphia, Pennsylvania

contact:JoEllen Weaver (215-214-1633)
JoEllen.Weaver@fccc.edu
GIST tumors are commonly associated
with mutations in genes referred to as
c-KIT and PDGFRalpha. This is much
less common in pediatric GIST
compared to adult GIST. Our laboratory
is using molecular genetic approaches
to study tumors without mutations
to understand their biologic differences
and to aid in identifying potential
therapies to treat these tumor types.

Constantine A. Stratakis MD, D(Med)S
Chief, Section on Endocrinology and Genetics
DEB, NICHD, National Institutes of Health
Building 10, CRC, Room 1-3330
10 Circle Drive, MSC1103
Bethesda, MD 20892

Phone:301-496-4686/496-6683
Fax: 301-402-0574/480-0378
E-mail:
stratakc@mail.nih.gov 

Our goal is to identify genes and
therapies for familial GISTs and related
conditions in the context of
inherited syndromes that are not due
to the known KIT and PDFGRA mutations.

 



back to top