Treatments for GIST

Patients with GIST cancer can receive effective treatments today.  For an outline of experts' treatment recommendations for GIST, see the NCCN documents listed first on our Best Links page.

Current Treatments

• Surgery - Surgery is the first step in treatment for GIST, and it is often curative.
• Imatinib (Gleevec) - Imatinib (Gleevec) is FDA-approved for treatment of unresectable and metastatic GIST, as well as for prevention of recurrence of higher-risk GISTs (adjuvant therapy).
• Sunitinib (Sutent) - Sunitinib (Sutent) is FDA-approved for treatment of GIST resistant to imatinib/Gleevec and for patients who are intolerant of imatinib/Gleevec.
• Hepatic artery embolization - Embolization is a surgical procedure for treatment of liver metastases of GIST.
• Radiofrequency ablation - RFA is a surgical procedure for treatment of liver metastases of GIST.
• Current Treatment Directions - overview and list of consensus documents

• GIST Patients' Right to Treatment - the Bad Nauheim Declaration, endorsed by GIST Support International, for the right of all GIST cancer patients to receive up-to-date treatment.

Emerging Treatments

• Emerging Treatments covers drugs in pre-clinical development and in clinical trials.

Clinical Trials

• Clinical Trials informs you about current trials for gastrointestinal stromal tumor plus things to consider before signing up for a trial.  This page includes a table showing all clinical trials for GIST, plus maps of locations of trials for GIST cancer.