GIST Support International - logo

GIST Support International - Tyrosine Kinase Inhibitors
GIST Imagery

Tyrosine Kinase Inhibitors

The following drugs under development are similar to approved GIST treatments imatinib (Gleevec) and sunitinib (Sutent) in that they inhibit the KIT and/or PDGFR growth factor receptors.  Some of them also inhibit vascular endothelial growth factor (VEGF) or its receptors for anti-angiogenic effects.

MLN518 

Vatalanib PTK787 

OSI-930

AZD2171

Amuvatinib (MP470)

TKI258

Masitinib (AB1010)

Crenolanib  (CP-868,596)

DCC-2618

 



back to top