Most of the following drugs are in clinical trials; a few are in pre-clinical development.  Note that some drugs are approved already for  treatment of other diseases, but are in trials for gastrointestinal stromal tumor.  Also, some approved drugs (such as imatinib and sunitinib) are in combination trials.

To view a table summarizing all the drugs and their targets, download this table (a printable Adobe pdf).

Drugs are categorized according to their targets in the following sections.  Click a category below to see its contents.

Inhibitors of KIT, PDGFR, or VEGF

HSP90 Inhibitors

Inhibitors of Pathways Downstream of KIT & PDGFR

Drugs in Combination

Other Trials

Drugs in Past Trials

Drugs to Watch