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Inhibitors of KIT, PDGFR, or VEGF
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Inhibitors of KIT, PDGRF, and VEGF
The following drugs under development are similar to imatinib (Gleevec) and sunitinib (Sutent) in that they inhibit the KIT and/or PDGFR proteins. Some of them also inhibit vascular endothelial growth factor (VEGF) or its receptors for anti-angiogenic effects.
nilotinib (Tasigna) formerly AMN107
