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Tumor size alone not always best for gauging treatment response

Not only can positron emission tomography (PET) help evaluate treatment for gastrointestinal stromal tumors (GIST) by revealing biologic changes such as how the tumor processes the fuel that makes it grow, but CT can indirectly reveal biologic changes as well by analyzing the tumor's density, say researchers from The University of Texas M. D. Anderson Cancer Center in Houston.

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ESMO: Tumor Shrinkage Doesn't Predict Response to Imatinib Therapy in Patients With Gastrointestinal Stromal Tumors

VIENNA, AUSTRIA -- November 4, 2004 -- Lack of progression is the most clinically significant predictor of a patient's response to imatinib in patients with gastrointestinal stromal tumours (GIST), a new analysis shows.

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Lack of progression is the most clinically significant measure of a patient's clinical benefit...

Abstract of presentation by G Demetri, M von Mehren, H Joensuu, S Finketstein, D Huse, B Kiese, K McDougal, S Dimitrijevic, GA Glendenning, C Blanke at the 2004 European Society for Medical Oncology congress.

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A phase I/II trial of the oral PKC-inhibitor PKC412 (PKC) and imatinib mesylate (IM) in patients (pts) with gastrointestinal stromal tumor (GIST)

Abstract of presentation by P Reichardt, D Pink, T Lindner, MC Heinrich, P Cohen, Y Wang, A Tsyrlova, A Yap, S Dimitirijevic, CD Blanke
at the 2004 European Society for Medical Oncology congress

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Biology of Gastrointestinal Stromal Tumors -- Corless et al. 22 (18): 3813 -- Journal of Clinical Oncology

From the Oregon Health & Science University Cancer Institute, Department of Pathology, and Division of Hematology and Oncology, Oregon Health & Science University and Veterans Affairs Medical Center, Portland, OR; and Department of Pathology, Brigham & Women's Hospital, Boston, MA

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CIW ENA 2004

CIW ENA 2004: "16th EORTC-NCI-AACR Symposium on 'Molecular Targets and Cancer Therapeutics'. "

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World Congress on Gastrointestinal Cancer

World Congress on Gastrointestinal Cancer (Webcasts)

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